Figure 1

The morphological changes of RBCs during retinal degeneration in RCS rats. Immunostaining for PKCα in the retinae of (a) control rats, and (b) RCS rats at P17, P30, P36, P60 and P90. The nuclei were stained using DAPI. Arrows indicate RBC dendrites growing into the ONL. (c) Number of RBC ectopic dendrites per field view (213 µm × 213 µm) in RCS rat retinae at P17, P30, P36, P60 and P90 (n = 5). (d) Same for length of ectopic dendrites (n = 5). ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; GCL, ganglion cell layer. Bars show means; error-bars, SEM. *p < 0.05; #p < 0.01.