Figure 7
Determination of the expression of inflammation-related molecules by quantitative real-time PCR in the hippocampus (a) and cerebral cortex (b) in mice with pilocarpine-induced acute status epilepticus. Anti-HMGB1, control IgG or PBS was administered intravenously when mice reached Racine stage 5 after pilocarpine. Brain samples were collected 24 h after antibody administration. The results were normalized to the expression of GAPDH and are expressed as the means ± SEM of 11 mice. *p < 0.05, **p < 0.01 compared with the sham group. &p < 0.05, &&P < 0.01 compared with the PBS control. #p < 0.05, ##p < 0.01 compared with the control IgG group (a,b).
