Table 3 Association between body mass index (BMI) and cognition, and imaging parameters in preclinical (CDR = 0) mutation carriers (MCs) and non-mutation carriers (NCs).

From: Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer’s disease

 

Outcome

β Coefficient (95% CI)

p value

MC

EYO

−0.263 (−0.552 to −0.026)

0.001

MMSE

−0.012 (−0.057 to 0.034)

0.895

Global PIB-uptake

−0.031 (−0.068 to 0.006)

0.032

LogMem II

1.724 (0.456 to 2.992)

0.017

NC

EYO

0.271 (−0.052 to 0.593)

0.037

MMSE

0.012 (−0.030 to 0.055)

0.969

Global PIB-uptake

−0.001 (−0.003 to 0.002)

0.0434

LogMem II

0.402 (−0.725 to 1.528)

0.397

  1. Note: Results are for linear regression. BMI was the predictor, adjusted for participant age, education and gender. Log Mem II = Logical Memory test, delayed recall; Global PIB-uptake = global cerebral Aβ burden as measured by 11C-Pittsburgh Compound-B PET.
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