Table 2 Thermodynamic parameters associated with the binding of CypA with CsA and AIF(370-394).

From: Structural and biochemical insights of CypA and AIF interaction

 

Single Site Binding Model

Nα

ΔGβ

ΔHβ

TΔSβ

KDγ

CypA-AIF(370-394)

1.0

−7.3

−6.2

1.1

6

CypA-CsA

1.0

−17.8

−29.6

−11.8

0.6

CypA + AIF(370-394)/CsA

1.4

−14.5

−14.7

−0.2

1.8

  1. αNumber of binding site, βExpressed in kcal/mol, γExpressed in μM.
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