Table 2 IL7RA genotypic distribution among MS cases and controls in the included studies.

IL7RA polymorphisms	First Author	Year	No. of Cases	No. of Controls	Cases			Controls			HWE	Power analysis*
IL7RA polymorphisms	First Author	Year	No. of Cases	No. of Controls	MM	MW	WW	MM	MW	WW	HWE	Power analysis*
rs3194051(8) (A > G)	Zhang	2005	667	558	54	235	378	23	230	305	0.01	0.98
	Gregory	2007	438	478	46	157	235	33	198	247	0.49	0.78
	Lundmark	2007	1785	2564	149	657	979	152	982	1430	0.33	0.99
	O'Doherty(1)	2008	208	413	18	85	105	30	163	220	0.87	0.15
	O'Doherty(2)	2008	463	531	31	178	254	36	206	289	1.00	0.05
	Akkad	2009	1279	857	102	511	666	63	346	448	0.80	0.11
	Bahlo	2009	2255	2308	152	868	1235	160	897	1251	0.96	0.07
	Kallio	2009	197	433	13	76	108	25	158	250	1.00	0.09
rs987107(6) (C > T)	Zhang	2005	528	563	53	186	289	34	228	301	0.33	0.93
	Gregory	2007	438	479	46	157	235	33	196	250	0.57	0.79
	Lundmark	2007	1779	2565	152	651	976	157	991	1417	0.35	0.99
	O'Doherty(1)	2008	207	413	17	83	107	29	160	224	1.00	0.12
	O'Doherty(2)	2008	462	527	31	178	253	35	202	290	1.00	0.05
	Jäger	2013	484	311	48	194	242	19	121	171	0.77	0.77
rs11567686(5) (A > G)	Teutsch	2003	176	176	19	79	78	18	75	83	0.86	0.12
	Broux	2010	65	33	8	29	28	2	12	19	1.00	0.48
	Hoe	2010	810	991	102	370	338	112	442	437	1.00	0.30
	Heidari	2011	100	100	18	51	31	16	47	37	0.84	0.24
	Haj	2015	202	244	49	99	54	58	102	84	0.02	0.70
rs11567685(8) (T > C)	Teutsch	2003	101	90	7	37	57	8	43	39	0.48
	Booth	2005	363	182	28	134	201	8	84	90	0.04
	Akkad	2009	1304	889	103	507	694	65	356	468	0.87
	Broux	2010	65	33	6	28	31	3	14	16	1.00
	Hoe	2010	810	991	56	313	441	71	389	531	1.00
	Heidari	2011	100	100	9	38	53	8	44	48	0.81
	Ibayyan	2014	200	200	4	59	137	10	78	112	0.57
	Haj	2015	219	258	19	80	120	28	87	143	0.0127

Note: MM: homozygous mutant genotype; MW: heterozygous mutant genotype; WW: wild genotype; NA: not available; power analysis*: rs3194051 (recessive model); rs987107 (recessive model); rs11567686 (dominant model).

Quick links

Search