Figure 3 | Scientific Reports

Figure 3

From: Heat shock protein70 is implicated in modulating NF-κB activation in alveolar macrophages of patients with active pulmonary tuberculosis

Figure 3

(A) Levels of HSP70 and NF-kB p65 in alveolar macrophages of TB patients (n = 6) quantified by western blot analysis in the absence or presence of a NF-kB inhibitor (PDTC). *p < 0.05 compared with control. (B) HSP70 levels in AM from TB patients (n = 4) quantified by western blot analysis in the absence or presence of a NF-kB inhibitor (PDTC) before or after anti-TB treatment for 3 M. *p < 0.05 compared with control. (C) Western blot analysis to quantify the expression of HSP70 and NF-κB p65 in AM from TB patients (n = 7) in the absence or presence of a p38 kinase (SB) or ERK kinase inhibitor (PD). *p < 0.05 compared with control. (D) Levels of HSP70 in HSP70 overexpressed AM (HSP70) from TB patients (n = 5) in the absence or presence of a p38 kinase (SB) or ERK kinase inhibitor (PD). *p < 0.05 compared with vector transfection control (Vector).

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