Table 1 Baseline and follow-up characteristics by depression status in the EpiDREAM study.

From: Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study

Traits

Categories

All

Depression Case

Non Depressed Control

P-valuec

Baseline Characteristics

Sex n (%)

Female

10598 (61.0)

2428 (75.8)

8170 (57.6)

<0.001

Male

6777 (39.0)

775 (24.2)

6002 (42.4)

Glycemic status n (%)

NGT

7431 (42.8)

1439 (44.9)

5992 (42.3)

0.006

IFG OR IGTb

7386 (42.5)

1339 (41.8)

6047 (42.6)

Type 2 diabetes

2558 (14.7)

425 (13.3)

2133 (15.0)

Age Mean ± SD (n)a

 

52.66 ± 11.37 (17375)

51.08 ± 10.55 (3203)

53.01 ± 11.52 (14172)

<0.001

BMI Mean ± SD (n)a

 

30.16 ± 6.22 (17369)

31.59 ± 6.78 (3201)

29.84 ± 6.04 (14168)

<0.001

Ethnicity n (%)

South Asian

2754 (15.8)

191 (6.0)

2563 (18.1)

<0.001

East Asian

225 (1.3)

23 (0.7)

202 (1.4)

European

9363 (53.9)

1748 (54.6)

7615 (53.7)

African

1247 (7.2)

225 (7.0)

1022 (7.2)

Latin American

3287 (18.9)

914 (28.5)

2373 (16.8)

Native North American

499 (2.9)

102 (3.2)

397 (2.8)

Total

17375 (100)

3203 (100)

14172 (100)

Follow-up Characteristics

Glycemic status n (%)

dNGT at baseline and follow-up

2,554 (25.7)

476 (25.8)

2,078 (25.7)

0.21

dIncident IFG/IGT (%)

971 (9.8)

179 (9.7)

792 (9.8)

dIncident T2D N (%)

1,270 (12.8)

262 (14.2)

1,008 (12.5)

Other participants followed-up (%)

5,135 (51.7)

928 (50.3)

4,207 (52.0)

  1. aSD = standard deviation. bNGT = normal glucose tolerance; IFG = impaired fasting glucose; IGT = impaired glucose tolerance. c P are reported for unadjusted univariable analyses (Chi-square or Student T-tests. dGlycemic status based on OGTT.