Table 2 Euglycemic hyper-insulinemic clamp data in the Low-MCRI and High-MCRI groups.

From: Correlates of insulin clearance in apparently healthy non-obese Japanese men

 

Total

Low-MCRI

High-MCRI

p value

n

49

25

24

 

SSSI at first step (μU/mL)

19.2 ± 3.5

20.6 ± 2.7

17.8 ± 3.8

0.005

SSSI at second step (μU/mL)

35.1 ± 7.8

39.8 ± 3.4

32.9 ± 4.3

<0.001

Basal EGP (mg/m2·min−1)

80.6 ± 6.4

78.6 ± 5.1

82.5 ± 7.1

0.032

%reduction of EGP at first step (%)

71.7 ± 15.8

74.9 ± 15.4

68.3 ± 15.8

0.144

%reduction of EGP at second step (%)

89.5 (82.2–93.9)

87.1 (84.1–93.0)

89.7 (78.2–96.4)

0.274

%reduction of EGP/SSSI at first step (%/μU·ml−1)

3.7 ± 1.0

3.7 ± 0.9

3.7 ± 1.2

0.967

Rd at first step (mg/kg FFM·min−1)

4.4 ± 1.2

4.2 ± 1.1

4.6 ± 1.3

0.262

Rd at second step (mg/kg FFM·min−1)

8.6 ± 2.0

8.1 ± 1.7

9.0 ± 2.2

0.098

Rd /SSSI at second step (mg/kg FFM·min−1 μU−1·ml)

0.22 (0.19–0.29)

0.20 (0.18–0.23)

0.29 (0.22–0.33)

<0.001

  1. Data are mean ± SD or median (interquartile range).
  2. SSSI; steady state serum insulin, EGP; endogenous glucose production, Rd; rate of disappearance.