Table 2 Proteins significantly regulated following RAPTA-EA treatment determined from FITExP analysis of MCF-7 and MDA-MB-231 cells.
From: Expression proteomics study to determine metallodrug targets and optimal drug combinations
Protein | Acronym | P-value | Regulation |
|---|---|---|---|
Heat shock 70 kDa protein 1A/1B | HSPA 1A/1B | 2.46E-05 | Up |
Heme oxygenase 1 | HMOX1 | 7.44E-05 | Up |
TRAF-type zinc finger domain-containing protein 1 | TRAFD1 | 5.94E-04 | Up |
Sulfiredoxin-1 | SRXN1 | 2.17E-03 | Up |
Thioredoxin reductase 1, cytoplasmic | TXNRD1 | 2.21E-02 | Up |
DnaJ homolog subfamily B member 4 | DNAJB4 | 3.52E-02 | Up |
Flavin/biliverdin reductase (NADPH) | BLVRB | 4.47E-02 | Up |
Glucose-6-phosphate 1-dehydrogenase | G6PD | 4.48E-02 | Up |
