Figure 4 | Scientific Reports

Figure 4

From: Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

Figure 4

Chronic ER stress results in a sustained accumulation of cytosolic calcium. MIA PaCa-2, S2-VP10, and S2-013 cells treated with (A) known ER stress inducers and measured cytosolic calcium after 24 hours of treatment, and (B) mithramycin and measured cytosolic calcium after 24 hours of treatment, and (C) silenced with siSp1 measured cytosolic calcium after 24 hours of transfection.

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