Figure 3

Structural characterization of proteins encoded by lineage-specific genes and ORFs. Visual summary of the characterization made with Quick2D⁵⁰ on MCOX2, F-ORF, M-ORF, and the putative proteins encoded by the ORFs CmonM_UR_24_11 and Atra_UR_21_9 from Hyridella menziesii, Cumberlandia monodonta, and Anodontites trapesialis mtDNAs. Complete Quick2D outputs are displayed in Supplementary Information 5. In each panel, on the X axis are the amino acid positions of the protein, while on the Y is the support for each feature (described below) shown in terms of how many methods indicated a certain characteristic at a given position. Colour code of features: full green areas, transmembrane regions; striped red areas, regions forming helices; striped blue areas, regions forming beta-sheets; purple lines, signal peptide signature; orange lines, disordered regions. The two grey squares on the background of panels (a) and (b) represent, from left to right, the boundaries of the conserved transmembrane and periplasmic domains of COX2.