Figure 1

Changes of serum creatinine levels over time. After severe IRI of both kidneys, a trend of elevation of serum creatinine level was noted at 6 hours (P = 0.052) but afterward, significantly elevated serum creatinine levels were noted at all time points as compared with the sham control (n = 6), with peak level at day 1 († indicates P < 0.001, * indicates P < 0.05).