Figure 3 | Scientific Reports

Figure 3

From: Vascular Remodelling Relates to an Elevated Oscillatory Shear Index and Relative Residence Time in Spontaneously Hypertensive Rats

Figure 3

Arterial wall thickening and extensive elastin degradation were demonstrated near the inner wall of the aortic arch and was accompanied by elevated OSI and RRT values in hypertensive and antihypertensive-treated SHRs. (a) Histological analysis of cross-sections of the ascending aorta and aortic arch was performed with H&E and VVG staining in the WKY-CON, SHR-CON, WKY-NIF, and SHR-NIF groups. Quantitative analysis of the regional vessel wall thickness is shown in the (b) outer wall and (c) inner wall of the ascending aorta and the (d) outer wall and (e) inner wall of the aortic arch. Values are presented as the mean ± SD. (n = 6). *P < 0.05, ***P < 0.001, vs WKY-CON. † P < 0.05, ††† P < 0.001, vs WKY-NIF. CON, control; NIF, nifedipine.

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