Figure 2 | Scientific Reports

Figure 2

From: Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer

Figure 2

(a) Structure-activity relationship (SAR) to design GDC-0449 analogs. (b,c) Cell cytotoxicity assay of MIA PaCa-2 and PANC-1 cells treated with free drugs. Percentage of viable cells were estimated by MTT assay. Data is shown as the mean ± S.D. of three separate experiments (Student t-test; *p < 0.05; **p < 0.001; n = 3).

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