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Figure 1

From: Single-cell pH imaging and detection for pH profiling and label-free rapid identification of cancer-cells

Figure 1

Schematic of colorimetric single-cell pH imaging and detection with two pH indicators. (a) Schematic of single-cell pH imaging and detection by combined use of bright-field microscope-based UV-Vis microspectroscopy and common pH indicators. A selected area single-cell absorption spectrum is collected by an optical microscope equipped with a portable spectrometer and an optical splitter with a small collecting area. (b) The structures of two pH indicators used in this study.

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