Figure 1 | Scientific Reports

Figure 1

From: Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model

Figure 1

RECK is downregulated during sequential progression of HBP carcinoma. (A) qPCR analysis shows that RECK and TIMP-2 are downregulated during sequential progression of cancer. Data are the mean ± SD of three independent experiments (N = 3). ♣p < 0.001, *p < 0.01, #p < 0.05 versus control. (B) Immunoblotting was performed to analyse the expression of RECK, TIMP-2, MMP-2 and MMP-9 in buccal pouch tissues. Data are the mean ± SD of three independent experiments (N = 3). ♣p < 0.001, *p < 0.01, #p < 0.05 versus control. (C)Immunohistochemical staining of RECK (20X).

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