Table 2 Longitudinal association between metabolic parameters and incident psoriasis.

From: Impact of metabolic status on the incidence of psoriasis: a Korean nationwide cohort study

 

Cases

Person-years

Incidence ratea

HR (95% CI)

Unadjusted

Age-, Sex-adjusted

MVa-adjusted

DM

555

135,950

4.08

1.36 (1.25–1.48)

1.14 (1.04–1.25)

1.15 (1.05–1.26)

HTN

1,622

400,572

4.05

1.42 (1.33–1.50)

1.15 (1.08–1.23)

1.15 (1.08–1.24)

Hyperlipidemia

570

133,457

4.27

1.42 (1.31–1.55)

1.24 (1.13–1.35)

1.24 (1.13–1.36)

BMI (kg/m2)

 <18.5

416

160,815

2.59a

0.88 (0.79–0.97)

0.93 (0.84–1.03)

0.92 (0.83–1.03)

 18.5–22.9

4,328

1,464,854

2.96

1

1

1

 23–24.9

2,701

856,269

3.15

1.07 (1.02–1.12)

1.01 (0.96–1.06)

1.01 (0.96–1.06)

 ≥25

3,609

1,085,134

3.33

1.13 (1.08–1.18)

1.05 (1.01–1.10)

1.05 (1.00–1.10)

Metabolic status

 MHNO

4,159

1,605,863

2.6

1

1

1

 MUNO

3,286

876,075

3.8

1.45 (1.38–1.52)

1.31 (1.24–1.38)

1.29 (1.22–1.37)

 MHO

1,152

445,914

2.6

1.00 (0.93–1.07)

0.96 (0.89–1.02)

0.95 (0.89–1.02)

 MUO

2,457

639,220

3.8

1.48 (1.41–1.56)

1.35 (1.28–1.42)

1.33 (1.26–1.41)

  1. aper 1000 person-years. HR, hazard ratio; CI, confidence interval; DM, diabetes mellitus; HTN, hypertension; BMI, body mass index; MHNO, metabolically healthy, non-obese; MUNO, metabolically unhealthy, non-obese; MHO, metabolically healthy, obese; MUO, metabolically unhealthy, obese.
  2. aMV includes age, sex, smoking, alcohol drinking, exercise, and income.