Figure 2
From: Examining the efficacy of intravenous administration of predatory bacteria in rats
Inflammatory protein profile within rat blood and organs in response to intravenous inoculation of predatory bacteria. ELISA analysis of IL-1β, IL-4, IL-5, IL-6, IL-10, IL-13, CXCL-1/KC, IFNγ, and TNF in response to tail vein injection with predatory bacteria relative to PBS control was performed. Rats were injected with PBS, B. bacteriovorus 109J, or M. aeruginosavorus (and also K. pneumoniae [Kp] as a control). Inflammatory proteins were assessed within the spleen, liver, kidney and blood at two, four, and 18 hours post-inoculation. Twelve rats per treatment group (seven for K. pneumoniae) were used at each time point. Data are combined from two independent experiments. Data represent means ± standard errors of the means. Significant differences between treatment groups and respective control were determined using ANOVA (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).
