Table 2 Prevalence of congenital malaria as detected by qPCR.

From: Diagnosing congenital malaria in a high-transmission setting: clinical relevance and usefulness of P. falciparum HRP2-based testing

Mother-child pairs

Congenital malaria

Cases detected

Prevalence (95% CI)

P-value*

Total mother-child pairs (n = 400)

16

4 (2.4–6.5)

—

Maternal peripheral infection

 Positive (n = 128)

14

10.9 (6.1–17.7)

<0.001

 Negative (n = 262)

2

0.8 (0.1–2.7)

 

Placental infection

 Positive (n = 137)

14

10.2 (5.7–16.6)

<0.001

 Negative (n = 259)

1

0.4 (0.0–2.1)

 

Mother-child pairs according to gravidity

 Primigravidae (n = 68)

3

4.4 (0.9–12.4)

0.980

 Secundigravidae (n = 74)

3

4.1 (0.8–11.4)

 

 Multigravidae (n = 258)

10

3.9 (1.9–7.0)

 
  1. * P value determined by Fisher’s exact test.
  2. CI, confidence interval.
Back to article page