Figure 2 | Scientific Reports

Figure 2

From: Up-regulation of long non-coding RNA XLOC_010235 regulates epithelial-to-mesenchymal transition to promote metastasis by associating with Snail1 in gastric cancer

Figure 2

Over-expression of XLOC_010235 promotes GC cell invasion and metastasis by affecting EMT. (A,B) Analysis of E-cadherin, N-cadherin, Vimentin, MMP-2 and MMP-9 expression following the treatment of MKN-1 cells with scrambled si-RNA and si-XLOC_010235, and the treatment of SGC-7901 cells with empty vector and pcDNA-XLOC_010235 by q-PCR. (C,D) Analysis of E-cadherin and Vimentin expression in MKN-1 cells treated with si-XLOC and SGC-7901 cells treated with pcDNA-XLOC by western blot and immunofluorescence. All experiments were performed in triplicate. Bars: SD. Bars: SD; *p < 0.05 and **p < 0.01.

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