Table 2 Associations of a SIX1/SIX6 locus and circumpapillary retinal nerve fibre layer thickness including 4 sectors.

From: Association of SIX1/SIX6 locus polymorphisms with regional circumpapillary retinal nerve fibre layer thickness: The Nagahama study

CHR	SNP	BP*	Gene	Minor Allele*	Other Allele*	Global		Temporal		Superior		Nasal		Inferior
CHR	SNP	BP*	Gene	Minor Allele*	Other Allele*	Beta	P†	Beta	P†	Beta	P†	Beta	P†	Beta	P†
14	rs140399719_T_C	60940196	SIX1/SIX6	T	C	−0.76	0.30	−0.69	0.42	1.48	0.22	−1.40	0.11	−2.42	0.056
14	rs144039268_G_T	60940392	SIX1/SIX6	G	T	−0.09	0.92	0.63	0.50	0.62	0.65	−0.75	0.45	−0.85	0.55
14	rs148908311_T_A	60941172	SIX1/SIX6	T	A	0.24	0.80	−1.02	0.35	2.43	0.12	0.24	0.84	−0.68	0.68
14	rs10138913_C_T	60943106	SIX1/SIX6	C	T	−0.46	0.18	−0.72	0.065	−0.09	0.87	0.29	0.48	−1.31	0.027
14	rs33912345_A_C	60976537	SIX1/SIX6	A	C	−0.52	0.18	−1.11	0.013	−0.23	0.71	0.67	0.15	−1.41	0.035
14	rs76172201_T_A	60989902	SIX1/SIX6	T	A	−0.38	0.65	0.93	0.34	−0.08	0.95	−1.78	0.08	−0.60	0.68
14	rs17097602_T_C	60997130	SIX1/SIX6	T	C	0.40	0.23	0.45	0.24	0.21	0.70	−0.11	0.79	1.03	0.073
14	rs1955691_G_A	61004128	SIX1/SIX6	G	A	0.03	0.95	0.37	0.47	−0.27	0.71	−0.32	0.55	0.34	0.66
14	rs1010053_A_G	61005625	SIX1/SIX6	A	G	−0.33	0.31	−0.50	0.18	−0.19	0.73	0.41	0.30	−1.06	0.061
14	rs12587483_A_G	61021885	SIX1/SIX6	A	G	0.38	0.26	0.35	0.37	0.08	0.88	−0.26	0.53	1.34	0.022
14	rs10133871_A_C	61063771	SIX1/SIX6	A	C	0.16	0.67	0.52	0.24	0.21	0.74	−0.06	0.90	−0.02	0.98
14	rs77636526_A_G	61077496	SIX1/SIX6	A	G	−2.25	0.046	−2.59	0.046	−0.88	0.63	−2.85	0.036	−2.67	0.17
14	rs79319089_A_T	61080521	SIX1/SIX6	A	T	−0.52	0.50	−0.65	0.47	0.20	0.88	−0.20	0.83	−1.43	0.28
14	rs75320987_C_T	61085911	SIX1/SIX6	C	T	0.82	0.15	0.70	0.28	−0.02	0.98	1.06	0.12	1.52	0.12
14	rs2057136_T_A	61106019	SIX1/SIX6	T	A	0.29	0.48	0.31	0.52	0.09	0.90	−0.12	0.80	0.90	0.21
14	rs117183588_T_A	61120441	SIX1/SIX6	T	A	−0.74	0.35	−1.02	0.26	0.62	0.64	−1.50	0.12	−1.06	0.44
14	rs7153648_C_G	61122526	SIX1/SIX6	C	G	0.20	0.61	0.44	0.32	0.14	0.83	−0.43	0.36	0.65	0.34
14	rs73309474_C_A	61124161	SIX1/SIX6	C	A	−1.06	0.21	−1.76	0.070	−0.11	0.94	−1.15	0.26	−1.20	0.41
14	rs143331462_T_C	61124545	SIX1/SIX6	T	C	0.03	0.96	0.99	0.22	0.80	0.49	−0.82	0.33	−0.83	0.50
14	rs7143029_T_C	61127916	SIX1/SIX6	T	C	0.45	0.22	1.04	0.013	0.34	0.57	−0.28	0.52	0.71	0.26
14	rs12147345_C_T	61140406	SIX1/SIX6	C	T	0.48	0.19	1.08	0.010	0.42	0.49	−0.30	0.50	0.73	0.25
14	rs12147346_C_T	61140408	SIX1/SIX6	C	T	0.39	0.27	0.81	0.047	0.42	0.47	−0.32	0.46	0.66	0.28
14	rs10137383_T_A	61140517	SIX1/SIX6	T	A	−0.29	0.54	−0.81	0.13	−0.06	0.94	−0.09	0.88	−0.21	0.80
14	rs12589826_A_G	61143058	SIX1/SIX6	A	G	0.42	0.23	0.88	0.031	0.49	0.40	−0.31	0.46	0.64	0.29
14	rs2351179_C_T	61157015	SIX1/SIX6	C	T	−0.25	0.44	0.05	0.90	0.11	0.83	−0.48	0.23	−0.70	0.22
14	rs61991690_C_T	61160190	SIX1/SIX6	C	T	0.42	0.36	0.27	0.60	0.29	0.70	0.20	0.72	0.91	0.25

CHR, chromosome; SNP, single nucleotide polymorphism; BP, base pair.
*Positions and alleles are given relative to the positive strand of NCBI build 37 of the human genome.
^†Linear regression analyses were applied assuming additive effect of the per minor allele variant, adjusted for age and sex. Significant (P < 4.8 × 10⁻⁴) or suggestive (P < 0.0125) associations are shown in bold.

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Table 2 Associations of a SIX1/SIX6 locus and circumpapillary retinal nerve fibre layer thickness including 4 sectors.

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