Table 2 Circulating blood cell numbers before (pre) and after (post) airway allergen challenge with house dust mite extract.

From: Sublingual house dust mite immunotherapy has no impact on decrease of circulating erythrocytes upon airway allergen challenge in allergic rhinitis

 

placebo

low dose SLIT

high dose SLIT

Total

group 1

group 2

group 3

n = 22

n = 29

n = 26

n = 77

 

pre

post

p

pre

post

p

pre

post

p

pre

post

p

Erythrocytes x10 12 /l

5.06 ± 0.46

4.96 ± 0.46

*

4.66 ± 0.48

4.58 ± 0.47

**

4,80 ± 0,29

4,76 ± 0,31

*

4.83 ± 0.44

4.75 ± 0.44

***

Hemoglobin g/dL

14.78 ± 1.30

14.60 ± 1.22

n.s.

13.60 ± 1.35

13.45 ± 1.44

*

14,20 ± 1,04

14,20 ± 1,12

n.s.

14.14 ± 1.32

14.03 ± 1.35

*

Hematocrit

0.44 ± 0.03

0.43 ± 0.03

*

0.41 ± 0.04

0.40 ± 0.04

**

0,43 ± 0,03

0,43 ± 0,03

n.s.

0.43 ± 0.04

0.42 ± 0.04

***

MCV fl/cell

87.59 ± 5.54

87.86 ± 5.14

n.s.

88.52 ± 6.05

88.45 ± 6.46

n.s.

89,58 ± 3,62

89,50 ± 3,89

n.s.

88.61 ± 5.19

88.64 ± 5.30

n.s.

MCH pg/cell

29.23 ± 2.11

29.59 ± 2.36

*

29.34 ± 2.04

29.38 ± 1.99

n.s.

29,73 ± 1,69

30,04 ± 1,64

*

29.44 ± 1.94

29.66 ± 1.99

**

MCHC g/dl

33.41 ± 1.00

33.68 ± 1.62

n.s.

33.07 ± 0.80

33.34 ± 0.81

n.s.

33,04 ± 0,92

33,31 ± 0,97

n.s.

33.16 ± 0.90

33.43 ± 1.14

**

Leukocytes x10 9 /l

6.15 ± 1.28

7.40 ± 1.89

**

6.55 ± 1,80

7.59 ± 1.84

**

5,93 ± 1,49

7,25 ± 1,78

***

6.23 ± 1.57

7.42 ± 1.82

***

Absolute Counts (x10 9 /l)

Segmented

3.13 ± 0.98

4.46 ± 1.75

***

3.71 ± 1.59

4.51 ± 1.52

**

3,32 ± 1,07

4,48 ± 1,52

***

3.41 ± 1.28

4.49 ± 1.57

***

Eosinophils

0.29 ± 0.30

0.25 ± 0.30

*

0.27 ± 0.21

0.26 ± 0.18

n.s.

0,21 ± 0,10

0,20 ± 0,11

n.s.

0.26 ± 0.21

0.24 ± 0.20

n.s.

Basophils

0.05 ± 0.03

0.04 ± 0.02

n.s.

0.05 ± 0.02

0.04 ± 0.02

n.s.

0,05 ± 0,03

0,05 ± 0,03

n.s.

0.05 ± 0.03

0.04 ± 0.02

n.s.

Lymphocytes

2.22 ± 0.55

2.17 ± 0.42

n.s.

2.05 ± 0.69

2.22 ± 0.71

n.s.

1,91 ± 0,48

2,03 ± 0,48

n.s.

2.05 ± 0.59

2.14 ± 0.56

n.s.

  1. Values present mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001; n.s. not significant;
  2. SLIT sublingual immunotherapy, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration.
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