Table 2 Carnitine palmitoyl transferase 1a (CPT1a) mutations in humane populations.

From: Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

 

CPT1a mutation

% CPT1a activity

% people with mutation

Depression rates

Canadian population

Wild type

100%42

~0%39

16%44

Hutterites

2129 G to A → AA710 Gly to Glu

~0%38,39,40, 42

60%39

0.35%43

Inuits

1436 C to G → AA479 Pro to Leu

22%41, 42

98%57

3%44

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