Figure 1

Conditional Q-Q plots of nominal versus empirical −log₁₀ p-values (corrected for inflation) in schizophrenia (SCZ) below the standard GWAS threshold of p < 5 × 10⁻⁸ as a function of significance of association with agreeableness, openness, extraversion, neuroticism and conscientiousness at the level of −log₁₀(p) ≥ 1, −log₁₀(p) ≥ 2, −log₁₀(p) ≥ 3 corresponding to p ≤ 0.1, p ≤ 0.01, p ≤ 0.001, respectively. Blue line indicates all SNPs. Dotted line indicates the null hypothesis.