Figure 5
Analysis of cell fates after LINC00152 depletion. (a) Images from movies of HeLa cells after LINC00152 knockdown by 30 nM siPOOL showed prometaphase arrest followed by mitotic death, mitotic exit or cytokinesis failure. Some cells also underwent apoptosis at an early stage without prior mitotic arrest. Time depicts hours after transfection. Images were acquired at 20x magnification and scale bar represents 20 μm. (b) Left circle portrays the effect on cells 72 hours after transfection with siLINC00152 (compare with Fig. 4b). Right circle represents a quantification of the cell fates depicted in (A) occurring in phenotypic cells. N = 3.
