Figure 6
From: Effects of hMASP-2 on the formation of BCG infection-induced granuloma in the lungs of BALB/c mice

Lung tissue from BCG-infected BALB/c mice was stained for the presence of CD11b, CD3 by immunohistochemistry. (A~D) CD3 staining of infiltrating T cells in lung interstitium from 4 representative mice (×200). (E~H) CD11b staining of infiltrating macrophages from 4 representative mice. On day 21 after rAd-hMASP-2 administration, the lung lesions tissue showing strong staining for CD11b and CD3 in rAd-hMASP-2 group. (I,J) Mean integrated optical density (IOD) of CD11b, CD3 detemined by Image Pro-Plus according to the staining intensity by visual assessment, n = 5 per group. Data ± SD are from five independent experiments (n = 5).