Figure 4 | Scientific Reports

Figure 4

From: Somatic Tumor Mutations Detected by Targeted Next Generation Sequencing in Minute Amounts of Serum-Derived Cell-Free DNA

Figure 4

Detection of somatic variants in primary tumor and serum-derived cfDNA specimens. The variant frequency in percentages of somatic variants detected in the primary tumor (PT) and three consecutive cfDNA samples (either T1, T2 or T3) of the ten patients in the study. Recurrent somatic variants at unique genomic positions are connected by lines to visualize variant frequency between replicates. Somatic variants detected in the primary tumor and confirmed in one, two or three patient-matched cfDNA sample in respectively white, grey or black. Somatic variants absent from the primary tumor but detected in two cfDNA sample in purple.

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