Table 1 Baseline characteristics of the studied subjects according to their diabetic nephropathy stages.

From: Assessment of the diagnostic value of different biomarkers in relation to various stages of diabetic nephropathy in type 2 diabetic patients

Variables

All studied cohort

Nephropathy Sub-groups

All (467)

No nephropathy (200)

Nephropathy (267)

p-value

Microalbuminuria (184)

p-value

Macroalbuminuria (83)

p-value

Age (years) (±SD)

55.64 (±6.11)

54.93 (±5.93)

56.18 (±6.2)

0.029

56.47 (±5.83)

0.011

55.52 (±6.95)

0.471

DM Duration (years) (±SD)

18.26 (±5.59)

16.97 (±4.68)

19.22 (±6.02)

>0.001

19.08 (±5.99)

<0.001

19.54 (±6.13)

<0.001

Height (cm) (±SD)

160.91 (±9.21)

160.17 (±8.69)

161.46 (±9.57)

0.137

161.18 (±9.72)

0.283

162.06 (±9.25)

0.105

Weight (Kg) (±SD)

84.47 (±16.33)

84.28 (±15.19)

84.61 (±17.16)

0.830

84.93 (±17.15)

0.695

83.91 (±17.28)

0.855

BMI (Kg/m2) (±SD)

32.66 (±5.9)

32.90 (±5.69)

32.47 (±6.06)

0.438

32.69 (±5.88)

0.722

31.99 (±6.47)

0.238

Hip (cm) (±SD)

109.71 (±12.49)

109.60 (±11.75)

109.80 (±13.04)

0.869

110.13 (±12.35)

0.666

109.04 (±14.51)

0.732

Waist (cm) (±SD)

106.57 (±12.31)

105.80 (±12.03)

107.14 (12.5)

0.245

107.22 (±12.14)

0.252

106.98 (±13.34)

0.470

W/H ratio

0.97 (±.08)

0.97 (±.08)

0.98 (±.07)

0.120

0.98 (±.07)

0.279

0.98 (±.07)

0.090

SBP (mmHg) (±SD)

137.71 (±20.28)

130.27 (±16.97)

143.29 (±20.79)

<0.001

140.02 (±19.4)

<0.001

150.55 (±22.02)

<0.001

DBP (mmHg) (±SD)

74.01 (±11.2)

72.36 (9.95)

75.25 (±11.92)

0.004

74.60 (±11.27)

0.040

76.71 (±13.2)

0.008

eGFR ml/min 1.73 m2 body surface area (±SD)

69.88 (±20.82)

79.76 (±16.66)

61.65 (±20.38)

<0.001

66.50 (±19.25)

<0.001

50.17 (±18.38)

<0.001

ACR mg/g (±SD)

276.99 (±705.47)

10.44 (±10.23)

477.40 (±882.77)

<0.001

113.80 (±77.18)

<0.001

1293.28 (±1249.74)

<0.001

Male gender

212 (45.4%)

85 (42.5%)

127 (47.57%)

0.277

80 (43.48%)

0.847

47 (56.63%)

0.030

Family history of Diabetes

414 (88.65%)

180 (90%)

234 (87.64%)

0.426

160 (86.96%)

0.350

74 (89.16%)

0.831

Family history of Renal disease (%)

74 (15.85%)

32 (16%)

42 (15.73%)

0.975

32 (17.39%)

0.672

10 (12.05%)

0.401

Neuropathy (%)

236 (50.54%)

95 (47.5%)

141 (52.81%)

0.256

97 (52.72%)

0.307

44 (53.01%)

0.398

Retinopathy (%)

216 (46.25%)

62 (31%)

154 (57.68%)

<0.001

93 (50.54%)

<0.001

61 (73.49%)

<0.001

Vasculopathy (%)

83 (17.77%)

20 (10%)

63 (23.6%)

<0.001

39 (21.2%)

0.002

24 (28.92%)

<0.001

Hypertension (%)

329 (70.45%)

115 (57.5%)

214 (80.15%)

<0.001

141 (76.63%)

<0.001

73 (87.95%)

<0.001

Hyperlipidemia (%)

401 (85.87%)

164 (82%)

237 (88.76%)

0.029

160 (86.96%)

0.141

77 (92.77%)

0.020

Thyroid (%)

75 (16.06%)

41 (20.5%)

34 (12.73%)

0.036

27 (14.67%)

0.188

7 (8.43%)

0.016

  1. ACR: Albumin creatinine ratio; BMI: body mass index; DM: diabetes mellitus; DBP: diastolic blood pressure; eGFR: estimated glumerular filtration rate; SBP: systolic blood pressure; W/H ratio: waist to hip ratio.
  2. P value was calculated in reference to the patients without diabetic nephropathy.
Back to article page