Figure 1 | Scientific Reports

Figure 1

From: Therapeutic effects of matrine derivate MASM in mice with collagen-induced arthritis and on fibroblast-like synoviocytes

Figure 1

Effects of MASM administration on mice with CIA. Mice were injected with saline or the indicated concentrations of MASM on day 22 (1 day after booster immunization on day 21). (A) The chemical structure of MASM. The mean clinical arthritis scores (B) and the hind paw thicknesses (C) were determined on the indicated days after the primary immunization. (D) Representative photographs of the hind paws of CIA mice on day 42. (E) Representative photographs of 3D reconstruction of micro-computed tomography of the hind paws (right) of mice with CIA. (F) Bone Erosion scores in CIA groups. Values in (B), (C), (F) are mean ± SEM from a representative experiment (n = 10~15). *P < 0.05, **P < 0.01 versus CIA mice treated with saline.

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