Figure 4
From: Circulating microRNA-214 and -126 as potential biomarkers for canine neoplastic disease

Heatmap and hierarchical cluster analysis of circulating miR-214 and -126 levels. Levels of circulating miR-214 and -126, showing different profiles between epithelial and non-epithelial groups. Heatmap and dendrogram were illustrated by Ward’s method using JMP software version 12.3. Samples were classified into 4 clusters based on the indicated threshold line. Relative levels (−∆CT, relative to circulating miR-16) were normalised by the Z-score. Statistical significance between each category was calculated by the Chi-square test (**P < 0.01, ***P < 0.001).