Figure 4
Expression of the immune module in TCGA-BRCA dataset is related to an increase in immune cells and in proteins necessary to an active immune response. (a) – Pearson Correlation between the ESTIMATE Immune score and the Immune metagene in the TCGA-BRCA dataset, r2 = 0.73, p < 0.01. (b) – Heatmap representing a semi-supervised clusterization of the protein levels of SYK, LCK and cleaved Caspase 7 in TCGA-BRCA dataset ordered by the rank of the Immune metagene. The correlation of the proteins level with the Immune metagene for SYK is r = 0.41, for Lck is r = 0.51 and for cleaved Caspase 7 r = 0.51. p < 0.01. Immune metagene = Metagene formed by the expression of IKZF3, SCML4, SP140 and ZNF831.
