Figure 3
Heat map of most relevant pathways on DEMs. This heat map depicts the most significant and highly relevant pathways obtained using experimentally verified targets of differentially regulated miRNAs (DEMs). Information on different doses and time intervals is shown on the right side and relevant signaling are shown at the bottom. Information on two potential early and sensitive miRNA biomarkers (miR-34a-5p and miR-455-3p) and their associated signaling is given on the top two rows. The top two rows depict whether a given miRNA is predicted to regulate a selected pathway or not. The “green” and “gray” colors indicate either a pathway is present or absent respectively.
