Figure 7 | Scientific Reports

Figure 7

From: β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

Figure 7

β-lapachone inhibitors effectively attenuate tumour growth and the proliferation of breast cancer cells in a mouse xenograft model. (A) The nude mice 27 days after injections and the growth curves of tumours. (B) and (C). Tumour volumes according to treatment group. (D) HE staining of the necrosis foci and lymphocyte infiltration of the tumours are noted (200 × ). (E) The expression levels of E-cadherin, Ki-67, p-Akt, p-S6, and p-4EBP1 in the tumour tissues were assayed (200×). **P < 0.01 is based on the Student t test, GLM-Repeated measurment. All results are from three independent experiments. Error bars, SD.

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