Figure 2
PLS-DA model plots for the control group (red symbols) versus the groups treated with different concentrations of TCBPA (blue symbols). Cross-validated score plots of the pairwise comparison between the (a) control versus 25 μM, (c) control versus 50 μM, and (e) control versus 100 μM TCBPA-treated groups. Two groups in each score plot were separated along the first component. In the score plots, the confidence interval is defined by the Hotelling’s T2 ellipse (95% confidence interval), and observations outside the confidence ellipse are considered outliers. Loading plots of the pairwise comparison between the (b) control versus 25 μM, (d) control versus 50 μM, (f) control versus 100 μM TCBPA-treated groups. The metabolites with the largest intensities contributed to the clustering.
