Figure 3
From: RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes
Downregulation of genes involved in ribosomal pathway in sarcoidosis monocytes. Graphic illustration of pathway analysis of DE (log2-fold change with FDR < 0.05) genes related to ribosome in sarcoidosis monocytes. The pathway diagram is overlaid with the computed perturbation of each gene. The perturbation accounts both for the gene’s measured fold changes and for accumulated perturbation propagated from any upstream genes (accumulation). The color intensity corresponds to the level of upregulation (red) or downregulation (blue) of the DE genes in sarcoidosis monocytes versus healthy monocytes. Note: A number of genes encoding large and small ribosomal subunits were downregulated.
