Figure 5
From: RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes
Proteasome in sarcoidosis monocytes. Graphic illustration of pathway analysis of DE (log2-fold change with FDR < 0.05) genes related to proteasome and immunoproteasome in sarcoidosis monocytes. The pathway diagram is overlaid with the computed perturbation of each gene. The perturbation accounts both for the gene’s measured fold changes and for accumulated perturbation propagated from any upstream genes (accumulation). Note: Several genes involved in regulatory and core particles and immunoproteasomes were downregulated (blue) in sarcoidosis monocytes.
