Figure 3
From: Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
Amino acid substitutions in the aminergic toxins and their ancestors from the two evolutionary pathways. Sequences are following the time/tree topology of the aminergic toxins. MT7 and MT2 sequences are not shown in the ρ-Da1a pathway due to divergences in sequence and function. Amino acid substitutions are highlighted in the first pathway. MT1-MT3 evolutionary pathway is also illustrated. Color display is settled in order to emphasize amino acid conservation along the toxins. Stronger blue color indicates residue conservation among all sequences.
