Table 2 Characteristics of vitreomacular interface clusters in central retinal vein occlusion (CRVO).

From: Evaluating the impact of vitreomacular adhesion on anti-VEGF therapy for retinal vein occlusion using machine learning

 

Cluster 0 (non-VMA)

Cluster 1 (VMA)

p

N=

82

116

 

Baseline BCVA (mean +− SD)

58.35 +− 12.61

50.85 +− 15.52

0.0004

BCVA change at month 12 (mean +− SD)

9.40 +− 12.99

17.65 +− 13.61

0.0004

Baseline CRT (mean +− SD)

630.50 +− 78.50

707.36 +− 300.53

0.7471

CRT change at month 12 (mean +− SD)

−423.50 +− 125.50

−468.40 +− 353.92

0.8747

Baseline ILM-VIT distance (mean +− SD)

2.38 +− 2.47

13.71 +− 12.41

<0.0001

Number of ranibizumab injections (mean +− SD)

8.08 +− 2.74

8.32 +− 2.68

0.6470

 

Cluster 0 (non-VMA)

Cluster 1 (VMA)

Cluster 2 (VMA)

p

N=

44

68

86

 

Baseline BCVA (mean +− SD)

61.00 +− 11.57

54.90 +− 14.23

49.64 +− 15.32

0.0001

BCVA change at month 12 (mean +− SD)

8.41 +− 13.87

13.00 +− 13.65

17.85 +− 13.08

0.0059

Baseline CRT (mean +− SD)

630.50 +− 78.50

485.00 +− 0.00

729.60 +− 306.45

0.7208

CRT change at month 12 (mean +− SD)

−423.50 +− 125.50

−212.00 +− 0.00

−496.89 +− 362.02

0.7593

Baseline ILM-VIT distance (mean +− SD)

1.12 +− 0.75

4.57 +− 3.50

16.58 +− 13.05

<0.0001

Number of ranibizumab injections (mean +− SD)

8.00 +− 2.95

7.78 +− 2.55

8.64 +− 2.61

0.3026

 

Cluster 0 (non-VMA)

Cluster 1 (VMA)

Cluster 2 (VMA)

Cluster 3 (VMA)

p

N=

40

57

48

53

 

Baseline BCVA (mean +− SD)

61.56 +− 11.52

55.54 +− 13.26

49.67 +− 15.74

50.45 +− 15.35

0.0004

BCVA change at month 12 (mean +− SD)

8.97 +− 13.61

11.37 +− 12.89

20.13 +− 17.32

16.27 +− 9.71

0.0058

Baseline CRT (mean +− SD)

630.50 +− 78.50

485.00 +− 0.00

709.50 +− 367.10

743.00 +− 257.35

0.8855

CRT change at month 12 (mean +− SD)

−423.50 +− 125.50

−212.00 +− 0.00

−612.00 +− 441.35

−439.33 +− 298.76

0.8143

Baseline ILM-VIT distance (mean +− SD)

1.07 +− 0.73

4.35 +− 3.74

6.24 +− 3.73

22.56 +− 13.15

<0.0001

Number of ranibizumab injections (mean +− SD)

7.89 +− 2.95

7.77 +− 2.68

8.21 +− 2.94

8.94 +− 2.09

0.3290

  1. BCVA = best-corrected visual acuity; SD = standard deviation; CRT = central retinal thickness; ILM = internal limiting membrane; VIT = posterior vitreous boundary.
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