Figure 3
Effect of IL-37 administration on DCs and CD4+T cells in spleen of ApoE−/− mice. (A) Flow cytometry results of DCs (CD86+MHC-II+CD11c+) are shown. The numbers in upper right quadrants indicate positive percentages of these cells. Results of statistical analysis of DCs. (B) Flow cytometry results of Th1 (CD4+IFN-γ+), Th2 (CD4+IL-4+), Th17 (CD4+IL-17+), and Tregs (CD4+CD25+FOXP3+) are shown. The numbers in upper right quadrants indicate positive percentages of these cells. Results of statistical analysis of Th1 cells, Th2 cells, Th17 cells, and Tregs. Values are presented as the means ± SEM, n = 8. *p < 0.05, and **p < 0.01.
