Figure 2 | Scientific Reports

Figure 2

From: Overexpression of LINC00152 correlates with poor patient survival and knockdown impairs cell proliferation in lung cancer

Figure 2

qRT-PCR validation of LINC00152 expression in an independent data set (A–C) and LINC00152 expression in other tumors types (D). (A) Scatterplot indicating LINC00152 expression was higher in tumor (measured by RT-PCR, y-axis is fold change to mean of normal tissues, LUAD vs. normal, p < 0.001 by t test). (B) ROC curve indicated an excellent AUC (0.88) for classifying the 101 LUAD from 27 normal lung tissues based on LINC00152 expression. (C) Kaplan-Meier curve indicated higher LINC00152 expression was unfavorable for patient survival. (D) Comparison of LINC00152 expression in cancers (red) and matched normal (blue) tissues (mean + SEM, log2 of FPKM from RNA-seq data). Lung, bladder, breast, gastric, head and neck, kidney, liver, and thyroid cancers were significantly higher in tumor (vs. normal, t test, p < 0.05). Case number of each cancer is indicated. The original data was downloaded from miTranscriptome with modification.

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