Table 4 Plasma asymmetric dimethylarginine concentrations in users of specific proton pump inhibitors

From: Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance

 

Esomeprazole (n = 32)

Omeprazole (n = 40)

Rabeprazole (n = 23)

Pantoprazole (n = 21)

Lansoprazole (n = 18)

P-value

Age (years)

69 (62–73)

68 (62–75)

63 (59–69)

65 (60–73)

66 (61–73)

0.092

eGFR (mL/min/1.73 m2)

77 ± 20

73 ± 15

76 ± 15

82 ± 20

74 ± 15

0.401

ADMA (µmol/L)

0.57 (0.52–0.64)

0.58 (0.51–0.64)

0.55 (0.50–0.65)

0.57 (0.51–0.60)

0.53 (0.49–0.63)

0.748

  1. eGFR: estimated glomerular filtration rate (Modification of Diet in Renal Disease formula); ADMA: asymmetric dimethylarginine.
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