Table 2 Univariate and multivariate analyses of baseline RBP4 levels.

From: Retinol-binding protein-4 expression marks the short-term mortality of critically ill patients with underlying liver disease: Lipid, but not glucose, matters

Variants

Univariate analysis: β (95% CI of estimated β)

Univariate analysis: p values

Multivariate analysis: β (95% CI of estimated β)

Multivariate analysis: p values

Sex (male)

−4.78 (−11.2–1.6)

0.143

  

Age (yr)

0.236 (0.051–0.422)

0.013*

0.152 (−0.163–0.466)

0.341

BMI

−0.148 (−0.721–0.425)

0.611

  

Diabetes (yes)

7.93 (2.29–13.57)

0.006*

1.78 (−5.3–0.885)

0.618

Hypertension (yes)

8.55 (3.01–14.08)

0.003*

2.88 (−4.1–9.85)

0.412

Sepsis (yes)

3.83 (−1.54–9.2)

0.161

  

Liver cirrhosis (yes)

3.02 (−2.75–8.79)

0.303

  

Pulmonary disease (yes)

−4.32 (−6.02–5,15)

0.879

  

HOMA-IR

−0.21 (−0.69–0.26)

0.374

  

HbA1C (%)

0.609 (−1.97–3.18)

0.641

  

C-peptide (ng/dL)

0.492 (0.047–0.937)

0.03*

0.219 (0.192–0.619)

0.292

Uric acid (mg/dL)

1.53 (0.807–2.254)

<0.001*

0.669 (−0.368–1.706)

0.203

eGFR (mL/min/1.73 m2)

−1.34 (−0.175–0.093)

<0.001*

−0.131 (−0.196–0.065)

<0.001*

TC (mg/dL)

0.16 (0.097–0.223)

<0.001*

0.096 (0.02–0.173)

0.014*

TG (mg/dL)

0.087 (0.058–0.117)

<0.001*

0.023 (−0.016–0.062)

0.244

HDL (mg/dL)

0.091 (−0.224–0.406)

0.57

  

AST (U/L)

−0.002 (−0.005–0.001)

0.217

  

ALT (U/L)

−0.009 (−0.015–0.002)

0.007*

−0.002 (−0.009–0.005)

0.571

APRI

−0.051 (−0.13–0.027)

0.198

  

Albumin (mg %)

−1.56 (−0.825–0.11)

0.645

  

Bilirubin (total) (mg %)

−0.27 (−0.53–0.009)

0.043*

0.007 (−0.374–0.387)

0.972

r-GT (IU/L)

0.012 (−0.009–0.033)

0.25

  

HsCRP (mg/L)

0.061 (0.009–0.112)

0.022*

0 (−0.052–0.052)

0.991

WBC (103/uL)

0.055 (−0.197–0.306)

0.67

  

Platelets (103/uL)

0.035 (−0.011–0.081)

0.14

  

Hb (g/dL)

−1.34 (−2.8–0.123)

0.072

  

NLR

0.075 (−0.051–0.208)

0.264

  

PT (INR)

−8.525 (−11.288–5.762)

<0.001*

−5.05 (−9.2–0.89)

0.018*

  1. RBP4: retinol-binding protein-4; BMI: body mass index; MELD: model for end-stage liver disease; APACHE: acute physiology and chronic health evaluation; ICU: intensive care unit; HOMA-IR: homeostatic model assessment for insulin resistance; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; AST: aspartate aminotransferase; ALT: alanine aminotransferase; APRI: aspartate aminotransferase-to-platelet ratio index; r-GT: r-glutamyltransferase; HsCRP: high-sensitivity C-reactive protein; WBC: white blood cell count; NLR: neutrophil-to-lymphocyte ratio; PT: prothrombin time; INR: international normalized ratio.
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