Figure 4 | Scientific Reports

Figure 4

From: High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice

Figure 4

Additional behavioural data and analyses. (A) Mean velocity during probe trials in the Morris water maze. (B) Distance moved during a 20 min open field test. (C) Percentage of time spent freezing during baseline, the post-shock period and during the context test given one day after training in a contextual fear conditioning paradigm. (D) Exploration times (known object, novel object) in the context of an object place recognition test. (E) Latency to fall off an accelerating rotarod. (F) Body weight (at 12 weeks of age). CD = F1 offspring of control dams. FD = F1 offspring of dams that received the folic acid-supplemented diet prior to mating. Data are presented as mean ± S.E.M.; asterisks denote significant differences (*p < 0.05, **p < 0.01, ***p < 0.001; CD: n = 24, FD: n = 20).

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