Table 4 Distribution of Allele/Genotype Frequencies in Younger Controls from Central, Southern and Eastern China.
From: APOE gene polymorphism in long-lived individuals from a central China population
Central China n (%) | Southern China n (%) | Eastern China n (%) | p | |
|---|---|---|---|---|
Allele | ||||
ε2 | 26 (6.37) | 97 (9.58) | 209 (6.95) | 0.015 |
ε3 | 338 (82.84) | 803 (79.35)† | 2566 (85.36) | 0.000037 |
ε4 | 44 (10.78) | 112 (11.07)† | 231 (7.68) * | 0.001 |
Genotype | ||||
ε2/ε2 | 0 (0.00) | 4 (0.79) | 9 (0.60) | 0.457 |
ε2/ε3 | 24 (11.76) | 76 (15.02) | 167 (11.11) | 0.065 |
ε3/ε3 | 137 (67.16) | 328 (64.82)† | 1109 (73.79)* | 0.000257 |
ε4/ε2 | 2 (0.98) | 13 (2.57) | 24 (1.60) | 0.239 |
ε4/ε3 | 40 (19.61) | 71 (14.03) | 181 (12.04)* | 0.009 |
ε4/ε4 | 1 (0.49) | 14 (2.77)† | 13 (0.86) | 0.002 |
