Table 4 Correlations between Treg/Th17 and relevant cytokines and the Suzuki’s angiographic stage.
From: Association of increased Treg and Th17 with pathogenesis of moyamoya disease
Grade 2 (N = 15) | Grade 3 (N = 9) | P value | |
|---|---|---|---|
Treg | 3.745 (2.813, 4.598) | 5.420 (4.088, 7.443) | 0.0068** |
Th17 | 2.170 (1.650, 3.450) | 2.450 (1.785, 3.340) | 0.7526 |
TGF-β | 31.730 (28.020, 41.470) | 48.250 (30.800, 64.190) | 0.0112* |
IL-17 | 129.800 (95.800, 146.000) | 121.100 (93.390, 153.900) | 0.8537 |
Treg/Th17 | 1.825 (0.697, 2.222) | 2.746 (1.312, 3.132) | 0.0401* |
IL-10 | 12.830 (11.900, 14.740) | 13.150 (12.490, 13.760) | 0.8567 |
IL-6 | 8.420 (7.450, 11.770) | 8.420 (5.985, 17.350) | 0.5466 |
IL-23 | 12.280 (7.770, 15.800) | 9.650 (7.520, 17.560) | 0.9844 |
TNF-α | 16.740 (15.870, 18.500) | 16.680 (15.720, 17.310) | 0.3745 |
VEGF | 33.450 (13.910, 63.150) | 28.760 (17.940, 68.760) | 0.7744 |
ICAM-1 | 38.600 (31.750, 49.650) | 35.350 (26.490, 39.800) | 0.1294 |
VCAM | 187.900 (143.000, 222.000) | 132.600 (99.470, 210.900) | 0.1771 |
HMGB-1 | 59.000 (25.500, 106.000) | 66.000 (35.000, 185.000) | 0.3284 |
