Figure 1
From: Hatching enzymes disrupt aberrant gonadal degeneration by the autophagy/apoptosis cell fate decision
Alternative splicing of AcHEs. In silico structural analysis of putative proteins depicted significant structural differences among AcHE1a (A), 1b (B) and 2a (C), especially in protein folding pattern in C-terminal region. Note: yellow asterisk (*) indicates the astacin (red ribbon shaped) domain. Schematic diagram show the alternative splicing of AcHE1 and 2, where, black boxes represents exon and dotted line indicates intron (D). Strong male dominated methylation of AcHE1, and not AcHE2, (E) was observed in Japanese anchovy adult gonads. Note: The graphical data are presented as percent mean ± SE; asterisk ‘#’ denotes significant sexual differences at each loci (P < 0.01); N = 15 individuals per sex, randomly collected from three distinct mature fish population @ 5/population; and the schematic diagram depicting the general methylation profile in female/male gonad and putative ERE (oestrogen responsive element) and PRE (progesterone responsive element) sites.
