Figure 2
From: NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
Effect of β-Lap on pancreatic MPO activity and inflammatory changes during caerulein-induced AP. (A) Pancreatic MPO activity. (B,C) Pancreatic mRNA levels of MCP-1, NLRP3, and ASC measured using qRT-PCR. (D,E) Total pancreatic homogenates were obtained from each experimental group and pancreatic protein levels of NLRP3 and ASC were measured by ELISA, and blotted with anti-caspase-1. (F) Serum IL-1β levels analysed by ELISA. Each value represents the mean ± SD (n = 5). *P < 0.05, **P < 0.01.
