Figure 2
From: Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas
Bacterial signatures detected in oral cancer samples. (a) Pie charts showing the percentage of different groups and phyla of bacteria detected in oral cancer, matched (MC) and non-matched controls (NC). (b) The bacterial signatures that are detected with hybridization signal (g–r > 30) by PathoChip screen of 100 oral cancer samples and in MCs and NCs are shown and ranked according to decreasing hybridization signal (weighted score sum of all the probes per accession) and prevalence. (c) Figure c shows the heat map of the hybridization signal for the bacterial probes of bacterial genera a-xyz, labeled in figure b, detected by PathoChip screen with the cancer, matched (MC) and non-matched control (NC) samples. Samples were screened individually and in pools (marked ▪). (d) Figure d shows the association of molecular signatures of different bacterial genera with oral cancer and/or controls, represented as a venn diagram, and as colored bars.
