Figure 1 | Scientific Reports

Figure 1

From: Beta sitosterol and Daucosterol (phytosterols identified in Grewia tiliaefolia) perturbs cell cycle and induces apoptotic cell death in A549 cells

Figure 1

Cytotoxic effect of Grewia tiliaefolia (GT) leaf on A549 cells. (a–c) Cytotoxic effect of different solvent extracts of GT on MCF-7, PC-3 and A549 cells at 48 h by MTT assay. (d) Cytotoxic effect of various concentration of BGT on A549 cells at 24 h and 48 h. (e) LDH leakage in A549 cells during the treatment of BGT at indicated concentrations for 48 h. (f) Morphological changes of A549 cells during BGT treatment after 48 h. The arrow heads indicates that the cells undergoing apoptosis display a series of typical morphological features such as cell shrinkage, membrane blebbing, reduced cell intensity and formation of apoptotic bodies. The data are presented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01 vs control group

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