Table 2 Sputum-smear and culture conversion time in per protocol group i.e. patients who completed the treatment.
Week | Smear conversion till (in weeks) | P | Odds Ratio (95% C.I.) | Culture conversion till (in weeks) | P | Odds Ratio (95% C.I.) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MIP Arm (N = 328) | Placebo Arm(N = 314) | MIP Arm (N = 328) | Placebo Arm (N = 314) | |||||||||
Converted (Cumulative numbers) | % | Converted (Cumulative numbers) | % | Converted (Cumulative numbers) | % | Converted (Cumulative numbers) | % | |||||
2 | 175 | 53.35 | 153 | 48.7 | 0.24 | 1.2 (0.87–1.66) | 139 | 42.37 | 118 | 37.5 | 0.215 | 1.22 (0.87–1.69) |
4 | 234 | 71.34 | 216 | 68.78 | 0.48 | 1.13 (0.79–1.61) | 220 | 67.1 | 179 | 57.0 | 0.0002* | 1.86 (1.31–2.64) |
6 | 268 | 81.7 | 242 | 77.1 | 0.146 | 1.33 (0.89–1.98) | 257 | 78.35 | 215 | 68.47 | 0.0046* | 1.67 (1.15–2.41) |
8 | 281 | 85.67 | 261 | 83.1 | 0.37 | 1.21 (0.77–1.9) | 286 | 87.1 | 248 | 78.98 | 0.0054* | 1.8 (1.16–2.84) |
12 | 298 | 90.85 | 274 | 87.3 | 0.14 | 1.45 (0.85–2.48) | 301 | 91.77 | 269 | 85.67 | 0.014* | 1.86 (1.1–3.22) |
16 | 303 | 92.37 | 280 | 89.17 | 0.16 | 1.47 (0.82–2.64) | 303 | 92.37 | 270 | 85.98 | 0.009* | 1.97 (1.14–3.46) |
26 | 305 | 92.98 | 283 | 90.13 | 0.19 | 1.45 (0.79–2.67) | 306 | 93.29 | 275 | 87.58 | 0.0136* | 1.97 (1.1–3.58) |
35 | 306 | 93.29 | 283 | 90.13 | 0.15 | 1.52 (0.83–2.83) | 306 | 93.29 | 277 | 88.2 | 0.026** | 1.86 (1.03–3.39) |
36 | — | — | — | — | 309 | 94.2 | 280 | 89.17 | 0.02* | 1.97 (1.06–3.75) | ||
39 | 309 | 94.2 | 284 | 90.4 | 0.073 | 1.72 (0.91–3.3) | 309 | 94.2 | 280 | 89.17 | 0.02* | 1.97 (1.06–3.75) |
40 | — | — | — | — | — | 281 | 89.49 | |||||
Median Time (range) | 2 (2–39) | 2 (2–39) | 4 (2–36) | 4 (2–40) | ||||||||
